脑源性神经营养因子

脑源性神经营养因子
	; PDB rendering based on 1bnd.
有效结构
PDB	直系同源检索：PDBe, RCSB
PDB查询代码列表
	1B8M, 1BND
标识
代号	BDNF; MGC34632
扩展标识	遗传学：113505 鼠基因：88145 同源基因：7245 GeneCards: BDNF Gene
基因本体论描述
分子功能	· protein binding; · growth factor activity;
细胞成分	· extracellular region; · cytoplasmic membrane-bounded vesicle;
生物过程	· ureteric bud development; · anti-apoptosis; · nervous system development; · negative regulation of neuroblast proliferation; · axon guidance; · axon target recognition; · learning or memory; · feeding behavior; · neuron recognition; · glutamate secretion; · dendrite development; · regulation of metabolic process; · nerve development; · mechanoreceptor differentiation; · response to drug; · fear response; · negative regulation of neuron apoptosis; · positive regulation of neuron differentiation; · regulation of retinal cell programmed cell death; · regulation of synaptic plasticity; · inner ear development;
	Sources: Amigo / QuickGO
RNA表达模式
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直系同源体
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A+医学百科 >> 脑源性神经营养因子

脑源性神经营养因子（英语：Brain-derived neurotrophic factor）是人脑中的一种蛋白质，由脑源性神经营养因子基因生成。脑源性神经营养因子是神经营养因子中的一种，这种因子存在于人的神经系统中。

注释

Fawzi MH, Kira IA, Fawzi MM, Mohamed HE, Fawzi MM. Trauma profile in Egyptian adolescents with first-episode schizophrenia: relation to psychopathology and plasma brain-derived neurotrophic factor. J. Nerv. Ment. Dis.. January 2013, 201 (1): 23–9. doi:10.1097/NMD.0b013e31827ab268. PMID 23274291.
Vaynman S, Gomez-Pinilla F. Revenge of the "sit": how lifestyle impacts neuronal and cognitive health through molecular systems that interface energy metabolism with neuronal plasticity. J. Neurosci. Res.. September 2006, 84 (4): 699–715. doi:10.1002/jnr.20979. PMID 16862541.
van Praag H, Christie BR, Sejnowski TJ, Gage FH. [http//www.ncbi.nlm.nih.gov/pmc/articles/PMC23964/ Running enhances neurogenesis, learning, and long-term potentiation in mice]. Proc. Natl. Acad. Sci. U.S.A.. November 1999, 96 (23): 13427–31. PMID 10557337. PMC 23964.
Gómez-Pinilla F, Ying Z, Roy RR, Molteni R, Edgerton VR. Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity. J. Neurophysiol.. November 2002, 88 (5): 2187–95. doi:10.1152/jn.00152.2002. PMID 12424260.

Cotman CW, Berchtold NC. BDNF and Alzheimer's Disease-What's the Connection?. Alzforum: Live Discussions. Alzheimer Research Forum. 2004-01-28 [2008-08-21].
Patten-Hitt E. Brain-Derived Neurotrophic Factor (BDNF). Sciencexpress. The HDLighthouse, Huntingtons Disease: Information and Community. 2001-06-14 [2008-08-21].
Highfield R. Brain scans 'could reveal mental strength'. Science. Telegraph.co.uk. 2007-10-18 [2008-08-21] (原始内容存档於2008-05-31). "Low BDNF activity promotes resilience"