泛醇—细胞色素c还原酶(英语:Ubiquinol-cytochrome-c reductase,EC 1.10.2.2)在酶学中是指一种催化如下化学反应的酶:
- QH2 + 2 高铁细胞色素c Q + 2 亚铁细胞色素c + 2 H+
因此,此酶的两个底物分别是二氢醌(QH2)与高铁(Fe3+)细胞色素c,而其三个产物则分别是醌(Q)、亚铁(Fe2+)细胞色素c以及氢离子。
参考文献
- ↑ PDB 1ntz; Gao X, Wen X, Esser L, Quinn B, Yu L, Yu CA, Xia D. Structural basis for the quinone reduction in the bc1 complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc1 with bound substrate and inhibitors at the Qi site. Biochemistry. August 2003, 42 (30): 9067–80. doi:10.1021/bi0341814. PMID 12885240.
深入阅读
- Marres CM, Slater EC. Polypeptide composition of purified QH2:cytochrome c oxidoreductase from beef-heart mitochondria. Biochim. Biophys. Acta.. 1977, 462 (3): 531–548. doi:10.1016/0005-2728(77)90099-8. PMID 597492.
- Rieske JS. Composition, structure, and function of complex III of the respiratory chain. Biochim. Biophys. Acta.. 1976, 456 (2): 195–247. PMID 788795.
- Wikstrom M, Krab K, Saraste M. Proton-translocating cytochrome complexes. Annu. Rev. Biochem.. 1981, 50: 623–655. doi:10.1146/annurev.bi.50.070181.003203. PMID 6267990.
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