肿瘤坏死因子-α

· cytokine activity
· tumor necrosis factor receptor binding
· protein binding
· identical protein binding

· extracellular space
· plasma membrane
· integral to plasma membrane
· external side of plasma membrane
· cell surface
· membrane raft

· negative regulation of transcription from RNA polymerase II promoter
· MAPK cascade
· activation of MAPKKK activity
· activation of MAPK activity
· response to hypoxia
· cell activation
· positive regulation of cytokine production
· positive regulation of protein phosphorylation
· negative regulation of L-glutamate transport
· chronic inflammatory response to antigenic stimulus
· negative regulation of cytokine secretion involved in immune response
· positive regulation of chronic inflammatory response to antigenic stimulus
· positive regulation of humoral immune response mediated by circulating immunoglobulin
· skeletal muscle contraction
· glucose metabolic process
· apoptotic process
· anti-apoptosis
· induction of apoptosis
· activation of cysteine-type endopeptidase activity involved in apoptotic process
· transformed cell apoptotic process
· inflammatory response
· humoral immune response
· JNK cascade
· negative regulation of cell proliferation
· induction of apoptosis by extracellular signals
· induction of apoptosis by extracellular signals
· induction of apoptosis via death domain receptors
· response to mechanical stimulus
· response to virus
· response to salt stress
· organ morphogenesis
· negative regulation of gene expression
· negative regulation of alkaline phosphatase activity
· negative regulation of lipid storage
· positive regulation of necrotic cell death
· response to activity
· calcium-mediated signaling
· extracellular matrix organization
· sequestering of triglyceride
· positive regulation of protein complex assembly
· positive regulation of fever generation
· lipopolysaccharide-mediated signaling pathway
· negative regulation of interleukin-6 production
· positive regulation of chemokine production
· positive regulation of interferon-gamma production
· positive regulation of interleukin-6 production
· receptor biosynthetic process
· positive regulation of peptidyl-serine phosphorylation
· tumor necrosis factor-mediated signaling pathway
· positive regulation of heterotypic cell-cell adhesion
· positive regulation of NF-kappaB import into nucleus
· response to drug
· positive regulation of apoptotic process
· positive regulation of apoptotic process
· negative regulation of apoptotic process
· positive regulation of programmed cell death
· regulation of I-kappaB kinase/NF-kappaB cascade
· positive regulation of I-kappaB kinase/NF-kappaB cascade
· positive regulation of protein complex disassembly
· positive regulation of MAP kinase activity
· protein kinase B signaling cascade
· positive regulation of neuron apoptotic process
· negative regulation of growth of symbiont in host
· negative regulation of viral genome replication
· positive regulation of chemokine biosynthetic process
· positive regulation of interleukin-8 biosynthetic process
· positive regulation of nitric oxide biosynthetic process
· negative regulation of fat cell differentiation
· negative regulation of osteoblast differentiation
· positive regulation of osteoclast differentiation
· positive regulation of mitosis
· negative regulation of transcription, DNA-dependent
· positive regulation of transcription, DNA-dependent
· positive regulation of transcription from RNA polymerase II promoter
· positive regulation of transcription from RNA polymerase II promoter
· positive regulation of translational initiation by iron
· negative regulation of glucose import
· positive regulation of JNK cascade
· embryonic digestive tract development
· positive regulation of smooth muscle cell proliferation
· positive regulation of cytokine secretion
· regulation of insulin secretion
· positive regulation of synaptic transmission
· defense response to Gram-positive bacterium
· leukocyte tethering or rolling
· negative regulation of lipid catabolic process
· regulation of immunoglobulin secretion
· positive regulation of membrane protein ectodomain proteolysis
· positive regulation of sequence-specific DNA binding transcription factor activity
· positive regulation of NF-kappaB transcription factor activity
· positive regulation of protein transport
· response to glucocorticoid stimulus
· positive regulation of NFAT protein import into nucleus
· positive regulation of hair follicle development
· positive regulation of protein kinase B signaling cascade
· induction of necroptosis by extracellular signals
· positive regulation of vitamin D biosynthetic process
· positive regulation of calcidiol 1-monooxygenase activity
· epithelial cell proliferation involved in salivary gland morphogenesis
· regulation of branching involved in salivary gland morphogenesis
· negative regulation of branching involved in lung morphogenesis
· necrotic cell death
· positive regulation of ERK1 and ERK2 cascade
· cellular response to amino acid stimulus
· cellular response to nicotine
· cellular response to organic cyclic compound
· positive regulation of mononuclear cell migration
· positive regulation of podosome assembly
· extrinsic apoptotic signaling pathway
· positive regulation of protein localization at cell surface